Endocrine Abstracts

Introduction: The visceral adipose tissue-derived serine protease inhibitor (vaspin), a novel adipocytokine, has been widely reported to be associated with obesity and insulin resistance. Obesity induced chronic inflammatory process plays a pivotal role in insulin resistance and is characterized by the activation of NF-κB pathway and its target genes. The present study aims to investigate the effects of vaspin on NF-κB pathway and its target genes in basal and TNF-&#...